Transcript analysis of RNA extracted from tumour tissue showed alterations consistent with the mechanism of DAC-paracetamol synergy: upregulation of PTGS2 and CYP2E1 (Fig 6F) and down-regulation of TP63 and KRT5 (Fig 6G)
8(1): 15-21. Published online 2018 Jan 31
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While Western countries like the United States, United Kingdom, and Sweden report a high incidence of iatrogenic neurological conditions related to advanced therapeutics (e.g., immune checkpoint inhibitors, SSRIs, TNF- inhibitors), endemic parasitic infections such as neurocysticercosis remain a predominant neurological concern in parts of Africa, Asia, and Latin America due to poor sanitation and zoonotic exposure
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